MicroRNA let-7 in the spotlight: Role in innate immunity
نویسندگان
چکیده
Innate immunity forms the first line of host defense. It is quick and usually shapes the adaptive immune responses which clear off the pathogens. However, dysregulated innate immune responses can lead to excessive inflammation which causes significant damage to the host. As a result, innate immune responses are tightly regulated. In this review, we focus on mechanisms by which microRNA let-7 regulate innate immune responses and contribute in maintaining tissue homeostasis.
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